Seven weeks after he returned to the Panthers and six weeks after he made his first start of 2021, is back to the bench. Carolina has elevated back into the starting quarterback role for the Panthers' matchup against the Saints on Sunday. The Panthers are 6.5-point underdogs in the latest Week 17 NFL odds from Caesars Sportsbook.In the NFL's current COVID-19 J.R. Richard Jersey reality where the Omicron variant is spreading acro s the league, NFL spreads can change at a moment's notice as players drop in and out of lineups. How does the Panthers' change at quarterback compare with other changes around the league? All of the Week 17 NFL lines are listed below and .The model, which simulates every NFL game 10,000 times, is up over $7,100 for $100 players on top-rated since its inception six-plus years ago. The model enters Week 17 of the 2021 season on an incredible 134-96 run on top-rated NFL picks that dates back to the 2017 season. The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.Now, it has turned its attention to the latest and locked in picks for every NFL matchup. . Top Week 17 NFL predictionsOne of the model's strongest Week 17 NFL picks is that the (+6) cover the spread against the . While Arizona has cratered in recent weeks, including in a 30-12 lo s to the struggling Detroit Lions, the Cardinals still have potential heading into this game. The model projects a solid game from quarterback , who pa ses for almost 260 yards and runs for more than 30 in SportsLine's projections.SportsLine's model has the Cardinals covering the spread in well over 50 percent of simulations and has them winning straight-up well over 40 percent of the time. The point total, which sits at 51, Tyler Clippard Jersey goes under in more than 50 percent of simulations as well.SportsLine's model predicts Murray will have another up-and-down day, but will pa s for just over 260 yards with a better chance to throw two touchdowns than two interceptions. is also projected to finish with over 100 total yards and the Cardinals keep the game within a point on the road. Another one of its Week 17 NFL predictions: The (+3.5) cover against the on Monday Night Football. This could be veteran quarterback final home game with the Steelers. He has led the team to a 5-0-1 record in their last six home games and will play in front of a raucous crowd. The Steelers still have a shot at making the playoffs with a pair of wins to close the regular season.SportsLine's model is projecting Browns quarterback to throw another interception on Monday Night Football. As a result, the Steelers cover the spread in more than 60 percent of simulations.How to make Week 17 NFL picksThe model has also made the Anthony Gose Jersey call on who wins and covers in every other game on the Week 17 NFL schedule, and it's calling for a Super Bowl contender to go down hard. . So which NFL picks can you make with confidence, and which Super Bowl contender goes down hard? Check out the latest NFL odds below, then , and find out.Week 17 NFL odds, spreads, linesSunday, Jan. 2 at (-7, 44.5) Featured Game | Indianapolis Colts vs. Las Vegas Raiders Moneyline Spread Total IND LV at (-6, 36.5) Featured Game | Chicago Bears vs. New York Giants Moneyline Spread Total CHI NYG at (+13, 45.5) Featured Game | New York Jets vs. Tampa Bay Buccaneers Moneyline Spread Total NYJ TB at (-14.5, 44) Featured Game | Buffalo Bills vs. Atlanta Falcons Moneyline Spread Total BUF ATL at Washington (+4.5, 45.5) Featured Game | Washington Commanders vs. Yuli Gurriel Jersey Philadelphia Eagles Moneyline Spread Total WAS PHI at (+4, 50.5) Featured Game | Cincinnati Bengals vs. Kansas City Chiefs Moneyline Spread Total CIN KC at (-16.5, 41.5) Featured Game | New England Patriots vs. Jacksonville Jaguars Moneyline Spread Total NE JAC at (-3.5, 40) Featured Game | Tenne see Titans vs. Miami Dolphins Moneyline Spread Total TEN MIA at (+5.5, 46.5) Featured Game | Baltimore Ravens vs. Los Angeles Rams Moneyline Spread Total BAL LAR at (-7.5, 45.5) Featured Game | Los Angeles Chargers vs. Denver Broncos Moneyline Spread Total LAC DEN at (-12.5, 44) Featured Game | San Francisco 49ers vs. Houston Texans Moneyline Spread Total SF HOU Cardinals at Cowboys (-6, 51.5) Featured Game | Dallas Cowboys vs. Arizona Cardinals Moneyline Spread Total DAL ARI at (-6.5, 37.5) Featured Game | New Orleans Saints vs. Carolina Panthers Moneyline Spread Total NO CAR at (-7.5, 41.5) Featured Game | Seattle Seahawks vs. Detroit Lions Moneyline Spread Total SEA DET at (-13, 42.5) Featured Game | Jimmy Wynn Jersey Green Bay Packers vs. Minnesota Vikings Moneyline Spread Total GB MIN Monday, Jan. 3 Browns at Steelers (+3.5, 41) Featured Game | Pittsburgh Steelers vs. Cleveland Browns Moneyline Spread Total PIT CLE